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目的 寻求高炉锰铁冶炼致职业暴露人群锰中毒的防治对策。方法 用职业流行病学的方法对某公司高炉锰铁冶炼的职业卫生监督监测和职业暴露人群追踪 35年的资料进行分析研究。结果 车间空气中锰浓度最高 199.4mg/m3 ,最低 0 .0 34mg/m3 ,平均 2 .0 46mg/m3 。随着技术改造的不断深入 ,车间空气中锰浓度呈显著下降趋势。累计追踪观察 15 5 5例锰暴露人群 ,共诊断锰中毒 39例 ,患病率 2 .5 0 8%。发病工龄最短 3年 ,最长 34年 ,平均 14年。采取依地酸二钠钙 (CaNa2 EDTA)、二巯基丁二酸 (DMSA)、对氨基水杨酸 (PAS)等驱锰 ,辅以能量合剂、维生素和普鲁卡因封闭 ,中药扶正、助阳、补气及调离锰暴露岗位等综合措施 ,疗效肯定 ;脑血流图 (REG)、脑多普勒 (TCD)、神经行为功能等检验指标 ,对锰中毒的诊断有一定参考价值。结论 改善生产环境 ,加强健康监护 ,积极治疗中毒患者 ,将有助于预防锰中毒的发生 ,有助于锰中毒患者的康复
Objective To seek the prevention and cure measures of manganese poisoning caused by occupational exposure to blast furnace ferromanganese. Methods Occupational epidemiological methods were used to analyze and monitor the occupational health supervision and monitoring of a company’s ferromanganese blast furnace and the occupational exposure for 35 years. Results The highest concentration of manganese in the air of workshop was 199.4mg / m3 and the lowest was 0.344mg / m3 with an average of 2.046mg / m3. With the deepening of technological transformation, the manganese concentration in the air of the workshop showed a significant downward trend. A total of 15 5 5 Mn-exposed subjects were followed up for a total of 39 cases of manganese poisoning, with a prevalence of 2.508%. The shortest three years of service, the longest 34 years, an average of 14 years. Take calcium disodium edetate (CaNa2 EDTA), dimercaptosuccinic acid (DMSA), para-aminosalicylic acid (PAS) and other drive manganese, supplemented by energy mixture, vitamins and procaine closed, Fuzheng help Yang, qi and adjusting away from manganese exposure post and other comprehensive measures, efficacy is positive; cerebral blood flow diagram (REG), brain Doppler (TCD), neurobehavioral and other test indicators, the diagnosis of manganese poisoning have some reference value. Conclusions Improving the production environment, strengthening health care and actively treating patients with poisoning will help to prevent the occurrence of manganese poisoning and contribute to the rehabilitation of patients with manganese poisoning