~(201)Tl再注射心肌显像和再注射后延迟显像检测心肌存活的对比研究

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为了解201Tl再注射及再注射后延迟显像对心肌存活的检测能力,对62例心肌梗塞患者进行了201Tl运动、3~5小时再分布、201Tl再注射后16~35分钟及再注射后12~19小时延迟心肌断层显像。15例患者于显像后行经皮冠状动脉腔内成形术(PTCA),并于PTCA后重复运动再分布心肌显像。结果:62例患者运动再分布显像共有126个不可逆缺损节段,其中48个节段再注射后16~35分钟出现放射性填充,心肌存活检出率为381%(48/126);51个节段再注射后延迟显像出现再分布,心肌存活检出率为405%(51/126)。两种显像方案的检出率差异无显著性(χ2=016,P>005),但两者结合62个节段示有放射性填充,心肌存活检出率可提高到492%(62/126)。15例患者PTCA前共检出17个心肌存活节段,术后12个节段201Tl灌注改善,阳性预测率为706%;PTCA前检出11个梗塞节段,术后9个节段201Tl摄取无改善,阴性预测率为818%。结果表明:201Tl再注射与延迟显像心肌存活检出率无明显差别,但两者联合应用可提高检出率。 In order to understand the ability of TLD to detect myocardial viability after 201Tl reperfusion and reperfusion, 201Tl exercise was performed in 62 patients with myocardial infarction, redistributed within 3 to 5 hours, 16 to 35 minutes after 201Tl re-injection, and 12 ~ 19 hours delayed myocardial imaging. Fifteen patients underwent percutaneous transluminal coronary angioplasty (PTCA) after imaging, and were subjected to repeated exercise-redistribution myocardial imaging after PTCA. RESULTS: There were 126 irreversible defect segments in 62 patients with motion-redistribution imaging. Radiographic filling occurred in 16 to 35 minutes after re-injection in 48 segments. The detection rate of myocardial survival was 38.1% (48/126) After reperfusion of 51 segments, delayed imaging appeared redistribution, and the detection rate of myocardial survival was 405% (51/126). There was no significant difference in the detection rates between the two imaging modalities (χ2 = 016, P> 005), but the combination of the two showed radioactive filling in 62 segments. The detection rate of myocardial survival increased to 49%. 2% (62/126). Seventeen myocardial surviving segments were detected in 15 patients before PTCA. The perfusion of 201Tl was improved in 12 segments after PTCA, the positive predictive value was 70.6%. Eleven infarcted segments were detected before PTCA and nine segments 201Tl no improvement, negative predictive rate was 81  8%. The results showed that there was no significant difference in the detection rate of myocardial viability between 201Tl reperfusion and delayed imaging, but the combination of the two could improve the detection rate.
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