胆红素的测定是临床诊断的一项重要指标。目前,临床上测定胆红素多数采用重氮试剂法,影响因素很多。寻找新的测定方法具有现实意义。自1987年我们开始了胆红素氧化酶的研究,已从我国土样中筛选到一株疣孢漆斑菌J-1,培养后分离纯化,得到了胆红素氧化酶。此酶具有潜在的临床应用价值。本文主要介绍胆红素氧化酶的一些特性及血清胆红素酶法分析新方法。 Determination of bilirubin is an important indicator of clinical diagnosis. At present, the majority of clinical determination of bilirubin reagent using diazotization, many influencing factors. It is of practical significance to find a new measurement method. Since 1987, we started the study of bilirubin oxidase, and we have screened out a strain of Myrothecium verrucaria J-1 from soil samples of our country, isolated and purified after cultivation, and obtained bilirubin oxidase. This enzyme has potential clinical value. This article describes some of the characteristics of bilirubin oxidase and serum bilirubin enzymatic analysis of new methods.