严重的哮喘经肾上腺素、氨茶硷等药物治疗12小时以上仍不缓解者称为哮喘持续状态。导致哮喘持续状态的诱因常与下列因素有关:1.呼吸道感染;2.接触过量的抗原或刺激性物质的持续存在;3.气雾剂(尤其是异丙肾上腺素制剂)使用不当或过量;4.治疗不当(尤其是长期应用皮质激素突然中断);5.痰液粘稠不易咳出或支气管粘液栓塞;6. 年老体弱或有并发症(如酸中毒、肺不张、气胸等)。哮喘持续状态对病人威胁很大,必须紧急处理,其具体措施如下。一、立即根据病史、体检、化验(血尿常规、痰培养、电解质测定、血气分析)、心电图检查、胸部X线检查以明确诊断,弄清有无并发症,有无脱水及其程度,心肺功能,既往用药史,以便胸中有数,制定治疗方 Severe asthma by epinephrine, aminophylline and other drugs more than 12 hours of treatment is still not known as persistent asthma. Causes of persistent asthma are often associated with the following: 1. Respiratory infections; 2. Persistent exposure to excessive levels of antigens or irritants; 3. Improper or excessive use of aerosols, especially of isoproterenol; 4. Improper treatment (especially long-term use of corticosteroids suddenly interrupted); 5 sputum viscosity is not easy to cough or bronchial mucus embolism; 6 frail elderly or complications (such as acidosis, atelectasis, pneumothorax, etc. ). The persistence of asthma is very dangerous to patients and must be urgently addressed. The specific measures are as follows. First, immediately based on medical history, physical examination, laboratory tests (blood and urine, sputum culture, electrolyte determination, blood gas analysis), ECG, chest X-ray examination to confirm the diagnosis, with or without complications, with or without dehydration and the extent of cardiopulmonary function , The history of past medication, in order to countless, formulating treatment