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目的观察血液透析(HD)串联血液灌流(HP)的血液净化组合抢救各种急性重度中毒的临床效果。方法采用HD串联HP血液净化组合治疗抢救各种急性重度中毒患者90例,同时用单纯HD抢救作对照观察。结果HD串联HP治疗组抢救成功率达97.8%,比对照组的75.0%高(P<0.01),且昏迷者的清醒时间快,住院时间短,无明显毒副作用。结论HD串联HP血液净化组合抢救各种急性重度中毒患者成功率高,无明显毒副作用,值得在基层透析中心推广应用,有较高的社会效益。
Objective To observe the clinical efficacy of hemodialysis (HD) tandem hemoperfusion (HP) blood purification combination to rescue all kinds of acute severe poisoning. Methods Ninety patients with acute severe poisoning were treated by HD serial HP blood purification combined with HD rescue. Results The success rate of rescue in HD series HP was 97.8%, which was higher than that in control group (75.0%) (P <0.01). The recovery time of coma was shorter and hospital stay was shorter with no obvious side effects. Conclusion HD serial HP blood purification combined with salvage of various acute severe poisoning patients with high success rate, no obvious side effects, it is worth to promote the use of primary dialysis center, a higher social benefits.