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RNA干扰(RNA interference,RNAi)是指一种双链RNA(double-stranded RNA,dsRNA)分子在mRNA(messenger RNA)水平关闭相应序列基因的表达后,使其沉默或表达下调,从而达到抑制某种特定基因表达的目的,是一种序列特异性的转录后基因沉默[1]。RNA干扰主要通过双链RNA被核酸酶切成21~2
RNA interference (RNAi) refers to a double-stranded RNA (dsRNA) molecule at mRNA (messenger RNA) level off the corresponding sequence gene expression, the silence or downregulation, so as to achieve the inhibition of a The purpose of specific gene expression is a sequence-specific post-transcriptional gene silencing [1]. RNA interference is cleaved 21-2 by nuclease mainly through double-stranded RNA