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目的观察2型糖尿病(T2DM)患者甲状腺功能,并进行相关分析。方法以我院住院就诊的T2DM患者为研究对象,分析甲状腺功能及异常患病率,及与空腹血糖、餐后2h血糖、糖尿病病程和体重指数之间关系,并以我院健康体检者为对照,比较两组甲状腺功能、空腹血糖和餐后2h血糖、总胆固醇、甘油三酯、体重指数等区别。结果 T2DM患者甲状腺功能异常患病率为22%,健康对照者为8%,差异有统计学意义(P<0.01);两组比较空腹血糖、餐后2h血糖、体重指数、FT3、TSH,差异有统计学意义(P<0.05);两组比较总胆固醇和甘油三酯、FT4,差异无统计学意义(P>0.05);相关性分析中FT3、TSH与空腹血糖、餐后2h血糖、糖尿病病程和体重指数之间存在相关关系,FT4与空腹血糖、餐后2h血糖和体重指数之间存在相关关系(P<0.01)。结论 T2DM患者甲状腺功能异常患病率较高,病情越重、病程越长的患者更易发生,应重视甲状腺功能的常规检测。
Objective To observe the thyroid function in patients with type 2 diabetes mellitus (T2DM) and to analyze their correlations. Methods T2DM patients hospitalized in our hospital as the research object, to analyze the thyroid function and abnormal prevalence, and with fasting blood glucose, 2h postprandial blood glucose, duration of diabetes and body mass index, and in our hospital as a control The differences of thyroid function, fasting blood glucose and postprandial blood glucose, total cholesterol, triglyceride and body mass index were compared between the two groups. Results The prevalence of abnormal thyroid function was 22% in T2DM patients and 8% in healthy controls (P <0.01). The fasting blood glucose, postprandial blood glucose at 2 hours, body mass index, FT3, TSH, (P <0.05). There was no significant difference between the two groups in total cholesterol, triglyceride and FT4 (P> 0.05). Correlation analysis showed that FT3 and TSH were associated with fasting blood glucose, postprandial 2h blood glucose, The correlation between FT4 and fasting blood glucose, 2h postprandial blood glucose and body mass index were correlated (P <0.01). Conclusion The prevalence of abnormal thyroid function in patients with T2DM is higher, the more serious the disease and the longer the duration of disease are more likely to occur. The routine testing of thyroid function should be emphasized.