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目的 观察异丙酚无痛人工流产时静脉注射缩宫素对血压和心率的影响。 方法 将 90例Ⅰ级 (美国麻醉协会麻醉术前分级 )早期宫内妊娠的患者随机分为 3组 :A组 30例 ,应用 2～ 3mg/kg异丙酚和 1μg/kg枸橼酸芬太尼进行无痛人工流产术 ,手术后期注射缩宫素 1ml,于注射后的 3min内观察收缩压、舒张压和心率变化 ;B组 30例 ,用相同麻醉方法进行无痛人工流产 ,术中不用缩宫素 ,观察指标与方法同于A组 ;C组 30例 ,不用任何麻醉药物进行人工流产 ,在与A组相同的时间注射缩宫素 ,观察指标与方法同于A组。 结果 A组在注射缩宫素后 0 5min ,血压显著下降 ,心率显著增加 ,注射后 2 .5min时 ,血压和心率基本恢复到注射前水平。B组和C组无明显血压下降。 结论 异丙酚无痛人工流产时注射常规剂量缩宫素后可致血液循环短暂严重波动 ,应引起临床妇产科医师高度重视 ,特别是对心功能储备较差的患者更应关注。
Objective To observe the effects of oxytocin intravenous oxytocin on blood pressure and heart rate during painless artificial abortion. Methods Totally 90 patients with stage I (American Anesthesia Society preoperative anesthesia classification) patients with early intrauterine pregnancy were randomly divided into three groups: group A (30 cases), application of 2 ~ 3mg / kg propofol and 1μg / kg fenoflurate citrate Nigeria for painless abortion, the late postoperative injection of oxytocin 1ml, observed systolic blood pressure, diastolic blood pressure and heart rate changes within 3min after injection; B group of 30 patients with the same method of anesthesia painless abortion, surgery without Oxytocin, the observation indicators and methods with the A group; C group of 30 patients without any anesthetic drugs for abortion, injection of oxytocin at the same time with the A group, the same indicators and methods of observation in the A group. Results At 0 minute after injection of oxytocin in group A, the blood pressure decreased significantly and heart rate increased significantly. At 2.5 minutes after injection, the blood pressure and heart rate recovered to the level before injection. B and C group no significant drop in blood pressure. Conclusions The injection of oxytocin in conventional painless induced abortion may lead to severe short-term fluctuations in blood circulation, which should be paid more attention to by clinical gynecologists and physicians. In particular, patients with poor cardiac function reserve should pay more attention.