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为了探讨髂动脉内膜剥脱术后再狭窄的预防，将２８只兔随机分为苯那普利组和对照组，行右髂动脉内膜球囊剥脱术。术后３０天处死动物，作病理形态学检查及流式细胞术测定。结果表明，苯那普利组损伤血管内膜厚度小于对照组，而管腔面积大于对照组（Ｐ均＜０．００１）。治疗组血管壁细胞增殖期细胞数明显低于对照组（Ｐ均＜０．００１）。提示，苯那普利能抑制动脉球囊损伤后血管平滑肌细胞增殖，减轻内膜增生。
In order to investigate the prevention of restenosis after endarterectomy of iliac artery, 28 rabbits were randomly divided into benazapril group and control group, and the right iliac artery endarterectomy was performed. The animals were sacrificed 30 days after the surgery for histopathological examination and flow cytometry. The results showed that the intimal thickness of benazepril group was smaller than that of control group, while the lumen area was larger than that of control group (all P <0.001). In the treatment group, the number of cells in the vascular wall proliferative phase was significantly lower than that in the control group (all P <0.001). Tip, benazapril can inhibit arterial balloon injury vascular smooth muscle cell proliferation, reduce intimal hyperplasia.