水杨醇 (salicylalcohol,1 )及钠盐 (2 ) ,是合成抗炎和防治肝炎等药物的重要中间体 [1,2 ] 。作者在实验中发现文献报道[3,4 ] 的合成方法存在产率低、工艺复杂和成本高等问题 ,为此进行了如下工作 :(1 )甲醛气体法 [4 ]改为多聚甲醛解聚法 ;(2 )缩合溶剂甲苯改为乙酸丁酯 ;(3 Salicylalcohol (1) and sodium salt (2) are important intermediates in the synthesis of anti-inflammatory and anti-hepatitis drugs [1,2]. The author found in the experiment that the synthesis methods reported in the literature [3, 4] have the problems of low yield, complex process and high cost, and the following work has been done for this: (1) Formaldehyde gas method [4] Method; (2) condensation solvent toluene to butyl acetate; (3)