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该文用选择紊P突变鼠、ICAM-1突变鼠及缺乏表达选择素P和ICAM-1双突变鼠为动物模型,眼镜蛇毒因子(CVF)诱导小鼠肺组织损伤,再用抗I-CAM-1(CD45)单克隆抗体、大鼠抗小鼠选择素P(CD62P)单克隆抗体(RB40.34)及两种大鼠抗小鼠选择素E抗体(9A9和14D4)注射,观察特
In this study, we used the double-mutant mice with the mutation of P-mutation, ICAM-1 and the lack of expression of P-selectin and ICAM-1 as animal models. Cobra venom factor (CVF) induced lung injury in mice. -1 (CD45) monoclonal antibody, rat anti-mouse selectin P (CD62P) monoclonal antibody (RB40.34) and two rat anti-mouse selectin E antibodies (9A9 and 14D4)