目的 :提高对尿道腺癌的认识。方法 :报道 2例尿道腺癌 ,并结合有关文献讨论其起源、诊断和治疗。结果 :2例均行手术切除 ,术后病检确诊 ,无并发症 ,随访 5年未见复发。结论 :尿道腺癌起源尚未明确 ,诊断依赖于尿道镜检及病理检查 ,手术切除是较好的治疗方法 Objective: To improve the understanding of urethral adenocarcinoma. Methods: Two cases of urethral adenocarcinoma were reported and their origin, diagnosis and treatment were discussed in combination with relevant literatures. Results: Both cases underwent surgical resection and postoperative pathological examination was confirmed with no complications. No recurrence was observed after 5 years of follow-up. Conclusion: The origin of urethral adenocarcinoma is not yet clear, the diagnosis depends on urethral microscopy and pathological examination, surgical resection is a better treatment