【摘 要】
：
BACKGROUND Administrative data show that acute heart failure (HF) patients are older than those enrolled in clinical regis-tries and frequently admitted to non-cardiological settings of care.The purpose of this study was to describe clinical characteristi
【机 构】
：
Heart Failure Clinic,Division of Geriatric Medicine and Intensive Care Unit,Azienda Ospedaliero-Univ
论文部分内容阅读
BACKGROUND Administrative data show that acute heart failure (HF) patients are older than those enrolled in clinical regis-tries and frequently admitted to non-cardiological settings of care.The purpose of this study was to describe clinical characteristics of old patients hospitalised for acute HF in Cardiology,Internal Medicine or Geriatrics wards.METHODS Data came from ATHENA (AcuTe Heart failurE in advaNced Age) registry which included elderly patients (≥ 65 years) admitted to the above mentioned settings of care from December 1,2014 to December 1,2015.RESULTS We enrolled 396 patients,15.4％ assigned to Cardiology,69.7％ to Internal Medicine,and 14.9％ to a Geriatrics ward.Mean age was 83.5 ± 7.6 years (51.8％ of patients ≥ 85 years) and was higher in patients admitted to Geriatrics (P ＜ 0.001);more than half were females.Medical treatments did not differ significantly among settings of care (in a context of a low prescription rate of renin-angiotensin-aldosterone system inhibitors) whereas significant differences were observed in comorbidity patterns and management guidelines recommendation adherence for decongestion evaluation with comparison of weight and N-terminal pro-B-type natriuretic peptide levels on admission and at discharge (both P =0.035 and P ＜ 0.001),echocardiographic evaluation(P ＜ 0.001) and follow-up visits planning (P ＜ 0.001),all higher in Cardiology.Mean in-hospital length of stay was 9 ± 5.9 days,significantly higher in Geriatrics (13.7 ± 6.5 days) and Cardiology (9.9 ± 6.7 days) compared to Internal Medicine (8 ± 5.2 days),P ＜ 0.001.In-hospital mortality was 9.3％,resulting higher in Geriatrics (18.6％) and Cardiology (16.4％) than Internal Medicine(5.8％),P=0.001.CONCLUSIONS In elderly patients hospitalised for acute HF,clinical characteristics and management differ significantly accor-ding to the setting of admission.
其他文献
Hepatic encephalopathy is an often devastating complication of chronic liver disease, associated with high mortality and in-creased burden on patients and healthcare systems. Current agents (such as nonabsorbable disaccharides and oral anti-biotics) are o
Hepatocellular carcinoma (HCC) is one of the leading caus-es of cancer deaths worldwide and liver transplantation (LT) is the only potentially curative treatment. Over the years, Milan criteria has been used for patient selection. There is ongoing researc
The liver is frequently affected by severe acute respira-tory syndrome-coronavirus 2 (SARS-CoV-2) infection. The most common manifestations are mildly elevated alanine aminotransferase and aspartate aminotransferase, with a prevalence of 16-53％ among pati
To achieve the goal of the World Health Organization to eliminate viral hepatitis as a major public health threat by 2030, the Chinese Society of Infectious Diseases and the Chinese Society of Hepatology convened an expert panel in 2019 to update the guid
胆管癌是种恶性程度很高的消化道肿瘤,且超过一半的患者在诊断时已是疾病晚期,错失了手术的机会.光动力疗法(PDT)是一种局部消融方法,它使用系统性光敏剂,优先聚集在恶性细胞中,并被非热光激活,通过氧自由基介导的过程导致恶性细胞的破坏.胆管癌的PDT潜在治疗方案包括联合化疗、联合支架植入、复发肿瘤的术后治疗,或对患者进行治疗使肿瘤降期后行根治性手术.在治疗胆汁淤积的同时,PDT疗法可提高生存率和生活质量,并减少肿瘤生长.
围绝经期综合征(menopausal syndrome,MPS)是指女性绝经前后因激素波动所致的一系列躯体及精神心理症状,其根本原因是生理性、病理性或手术引起的卵巢功能衰竭或耗竭,并伴随着较为复杂的并发症.发病时间久,对女性的身心健康危害很大,属难治之证,现代临床主要以心理疏导和激素治疗作为主要手段,然不良反应和危险性也不可避免.中医药凭借其独特优势在MPS的治疗中起到了良好效果.文章对近几年内国内外文献进行回顾和分析,对其归纳总结并就其治疗机制进行综述.
The novel coronavirus disease 2019 (COVID-19) pandemic has impacted health care worldwide, with specific patient populations, such as those with diabetes, cardiovascular disease, and chronic lung disease, at higher risk of in-fection and others at higher
Liver fibrosis is a life-threatening disease, with challenging morbidity and mortality for healthcare systems worldwide. It imparts an enormous economic burden to societies, mak-ing continuous research and informational updates about its pathogenesis and
目的 探讨脾转移性肿瘤的临床病理学特征.方法 回顾性分析2012年1月～2020年12月中山大学孙逸仙纪念医院的56例脾转移性肿瘤患者的临床资料及病理学特征,并复习相关文献.排除累及脾的淋巴造血系统肿瘤.结果 脾肿瘤139例,占同时期我院脾手术病例的11.82％.脾淋巴造血系统肿瘤44例,非淋巴造血系统肿瘤95例,其中转移性肿瘤56例.脾转移性肿瘤占同时期我院脾手术病例的4.76％,占同时期我院脾肿瘤性病变的40.29％.56例脾转移性肿瘤患者中,男性26例,女性30例.发病年龄30～76岁,平均年龄53
五味子是中药中的食药两用之品,具有收敛固涩、益气生津、补肾宁心功效.现代药理研究发现五味子的多种有效成分,如木质素、多糖等均具有降糖作用.为此,通过近年来文献检索发现,五味子及其活性成分可显著降低模型动物体内丙二醛(MOD)含量,提高空腹胰岛素(FINS)和超氧化物歧化酶(SOD)含量,修复受损伤的胰岛B细胞,通过其抗氧化应激反应、抑制炎症反应、抗细胞凋亡、抗脂质过氧化等机制来发挥其降糖作用.因此,该文就五味子及其有效成分对糖尿病治疗作用及降糖机制研究进行综述,以期为五味子及其有效成分在防治糖尿病方面的深