论文部分内容阅读
目的了解山西省出生缺陷高发地区目前各种体表出生缺陷患病水平及流行特征。方法以人群为基础对山西省的4个县24种体表重大出生缺陷进行监测。结果2003年四个县共监测到孕满20周以上的出生11534名,总出生缺陷患病率分别为232.4/万。神经管畸形患病率为138.7/万,占全部出生缺陷病例的59.7%。患病率高于10/万的出生缺陷有7种,依次为:无脑儿(65.9/万)、脊柱裂(58.1/万)、脑积水(47.7/万)、多指(26.0/万)、腭裂(21.7/万)、脑膨出(14.7/万)、唇裂(10.4/万)。产妇文化程度低和女性胎婴神经管畸形的患病率显著增高。此外,居住在农村,妇女年龄不足20岁或30岁以上神经管畸形患病率有升高的趋势。结论神经管畸形仍然为山西省出生缺陷高发区最常见的先天畸形,目前其患病率仍然处于我国乃至世界最高的水平。居住在农村、文化程度低、怀孕年龄太小或较大的妇女生育出生缺陷儿的危险性较大。
Objective To understand the current prevalence and prevalence of birth defects in various birth defects in areas with high prevalence of birth defects in Shanxi Province. Methods Based on the population, 24 kinds of major birth defects in 4 major counties in Shanxi Province were monitored. Results In 2003, a total of 11534 births were detected in more than 20 weeks in four counties. The prevalence of total birth defects was 232.4 / million. The prevalence of neural tube defects was 138.7 / million, accounting for 59.7% of all cases of birth defects. There were 7 birth defects with a prevalence of over 10%, followed by anencephaly (65.9%), spina bifida (58.1%), hydrocephalus (477%), multiple finger (26.0% ), Cleft palates (21.7 / million), encephalocele (14.7 / million), cleft lip (10.4 / million). Low maternal education and female fetus baby the incidence of neural tube defects was significantly higher. In addition, women living in rural areas, women under the age of 20 or over the age of 30 the prevalence of neural tube defects have increased. Conclusions Neural tube deformity is still the most common congenital malformation in the high incidence area of birth defects in Shanxi Province. At present, the prevalence is still at the highest level in China and even in the world. Women living in rural areas, with a low level of education and who are too young or too pregnant, are at greater risk of having birth defects.