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目的探讨小儿肺炎支原体(MP)感染致传染性单核细胞增多综合征(IM)的临床特征。方法对ELISA方法检测MP-IgM均≥1∶160,EB病毒衣壳抗原VCA-IgM、IgG均为阴性而诊断为MP感染并发传染性单核细胞综合征的10患儿进行回顾性临床分析。结果发热、肝脾肿大、扁桃体肿大10例,扁桃体并白色渗出物7例,淋巴结肿大8例、眼睑水肿7例,肺炎6例,心肌损害1例。10例均未见皮疹。全部经阿奇霉素序贯治疗及护肝治疗9～16 d痊愈。结论 MP感染可并发传染性单核细胞增多综合征,临床表现为发热、咽痛、淋巴结肿大三联征、常伴肝脾肿大、肝功能异常,部分伴有其他器官功能损害。阿奇霉素治疗有效,预后良好。
Objective To investigate the clinical features of infectious mononucleosis syndrome (IM) in children with Mycoplasma pneumoniae (MP) infection. Methods Retrospective clinical analysis of 10 children diagnosed as MP infection and infectious mononuclear cell syndrome by ELISA was used to detect MP-IgM ≥1: 160, VCA-IgM and IgG were all negative. The results of fever, hepatosplenomegaly, tonsil enlargement in 10 cases, tonsil and white exudate in 7 cases, 8 cases of lymphadenopathy, eyelid edema in 7 cases, pneumonia in 6 cases, 1 case of myocardial damage. None of the 10 cases had a rash. All by azithromycin sequential treatment and liver protection 9 ~ 16d healed. Conclusion MP infection may be complicated by infectious mononucleosis syndrome, clinical manifestations of fever, sore throat, lymph node enlargement triple sign, often accompanied by hepatosplenomegaly, liver dysfunction, some accompanied by other organ dysfunction. Azithromycin effective treatment, the prognosis is good.