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目的 探讨妊娠期糖尿病视网膜病变的发病与进展因素。方法 随机检测 32例DR孕妇、 32例NDR孕妇和 32例正常孕妇的血糖、糖基化血红蛋白和果糖胺。结果 (1)妊娠期糖尿病视网膜病变的发病率为 1 4 4 % ;(2 )妊娠期糖尿病视网膜病变的进展率为 31 2 5 % ;(3)妊娠中期 ,DR孕妇组血中糖基化血红蛋白和果糖胺水平明显高于正常孕妇组 (P <0 0 5 ) ;(4)妊娠晚期 ,DR孕妇和NDR孕妇组血中糖基化血红蛋白和果糖胺水平明显高于正常孕妇组 (P <0 0 1)。结论 妊娠会促进糖尿病孕妇的视网膜病变加重 ,可能与血中糖基化血红蛋白和果糖胺水平增高有关。
Objective To investigate the incidence and progression of gestational diabetic retinopathy. Methods Blood glucose, glycosylated hemoglobin and fructosamine were randomly detected in 32 DR pregnant women, 32 pregnant women with NDR and 32 normal pregnant women. Results (1) The incidence of diabetic retinopathy in gestational age was 14.4%. (2) The progress rate of diabetic retinopathy in gestational age was 31 2 5%. (3) The levels of glycosylated hemoglobin (P <0.05). (4) The levels of glycosylated hemoglobin and fructosamine in DR pregnant women and NDR pregnant women were significantly higher than those in normal pregnant women (P <0 05) 0 1). Conclusions Pregnancy can promote the retinopathy in diabetic pregnant women, which may be related to the increase of glycosylated hemoglobin and fructosamine in blood.