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目的观察2%利多卡因与75%酒精湿敷在新生儿腰椎穿刺时的镇痛效果.方法将需要做腰椎穿刺术的新生儿87例,共104人次,随机分为观察组和对照组,各52人次,观察组取75%酒精和2%利多卡因各5 ml,混合摇匀侵入2 cm×2 cm棉片,制成利多卡因混合液镇痛棉.用镇痛棉在穿刺部位湿敷5min后,进行穿刺,对照组直接进行穿刺.使用美国Mount Sinai School of Medicine新生儿疼痛评估量表观察两组疼痛的发生率和程度.结果观察组疼痛发生率和疼痛程度低于对照组.结论2%利多卡因与酒精合用,制成镇痛棉,对腰椎穿刺有镇痛作用,可试行推广应用于新生儿的各种穿刺镇痛.“,”Objective To observe the influence of using 2% lidocaine and 75% alcohol to ease painful of lumbar puncture on neonatus .Methods eighty seven neonatus who were given 104 lumbar puncture,we randomly separate to observe group and control group. observe group receive hydropathic compress using 2% lidocaine and 75% alcohol before lumbar puncture . control group receive lumbar puncture with nothing. Using painful scale of evaluation on neonatus. Results the incidence of ache and the degree of ache in the observe group were lower than control group. Conclusion using 2% lidocaine and 75% alcohol can relieve painful of lumbar puncture on neonatus .