细菌感染是早产儿死亡的主要原因之一,需重症监护早产儿败血症发生率高达25％～50％,病死率约15％～20％。早产儿发生败血症时外周血多表现为中性粒细胞（NC）减少或缺乏（1）,其致病菌谱也多与严重粒细胞缺乏症病人相同（2）,本文将就早产儿NC的产生和功能特点及其与败血症的关系、应采取的对策做一综述。 Bacterial infection is one of the major causes of death in preterm infants. The incidence of sepsis in intensive care preterm infants is as high as 25% -50% and the mortality rate is about 15% -20%. Preterm infants with sepsis in peripheral blood showed more neutrophils (NC) reduction or lack of (1), the pathogenic bacteria spectrum and more patients with severe agranulocytosis (2), this article will preterm children with NC Produce and functional characteristics and its relationship with sepsis, the measures to be taken to review.