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缺血性卒中早期(在头两天时)用放血(250—650毫升)加低分子右旋糖酐进行快速血液稀释,在予测性对照试验中做了评价。52例随机用血液稀释疗法为一组,50例做对照为一组;两组在予后上有极大的差别。平均 Hb 从147下降到127g/1,细胞压积从43%降到37%,在病人的次血标样中,在头两天全血粘度(在剪切率为23秒~(-1)时)从7.0降到4.3cps。血液稀释后由反复输右旋糖酐来维持.血液稀释的病人,85%于头10天内较对照组的64%(P<0.025)神经学划分有明显地改进。在头三个月的病死率受血液稀释的影响很小.在存活者中,血稀组
Rapid hemodilution with bleedings (250-650 ml) plus dextran in the early stages of ischemic stroke (in the first two days) was evaluated in a predictive control trial. 52 cases of randomized hemodilution therapy for a group of 50 cases as a control group; the two groups after the great difference. The average Hb decreased from 147 to 127 g / l and the cell pressure decreased from 43% to 37%. In the patient’s secondary blood sample, whole blood viscosity (at a shear rate of 23 seconds -1) When) dropped from 7.0 to 4.3 cps. Repeated infusion of dextran after hemodilution was maintained in 85% of the patients in the blood dilution compared with 64% in the control group (P <0.025) within the first 10 days. The mortality in the first three months was minimally affected by hemodilution. Among the survivors, the blood thinning group