论文部分内容阅读
本实验采用毒性小的氯甲酸三氯甲酯代替毒性较强的光气做为氯甲酰化试剂,摸索出以6—APA 为起始原料合成氧哌嗪青霉素钠的工艺路线。
In this experiment, trichloromethylchloroformate with low toxicity as a chloroformate instead of the more toxic phosgene was developed to find out the technological route for the synthesis of piperacillin sodium with 6-APA as the starting material.