论文部分内容阅读
Fahr氏综合征,即纹状体一苍白球齿状核钙化,临床表现为癫痫发作、进行性痴呆等。有人报导甲状旁腺机能低下(HPT)者70～80%并发本病,一般认为钙代谢紊乱是重要的发病因素。随CT问世,颅内钙化检出率提高,发现HPT引起本病之比例越来越少。有钙磷代谢障碍者并非都能产生钙化。有人分析一组患者,遗传因素占5%神经系统疾病29%、HPT 37%、其他37%。本文结合3例报告,对本病发病机理进行探讨。三名患者皆为成年男性,幼年皆有脑膜脑炎史,11～36年后发生本病,表现为全身癫痫大发作或一
Fahr’s syndrome, a pale ball of the dentate nucleus calcification, clinical manifestations of seizures, dementia and so on. It has been reported hypoparathyroidism (HPT) who 70% -80% of the disease, the general thought that calcium metabolism disorders are an important risk factor. With the advent of CT, the detection rate of intracranial calcification increased and found that HPT caused less and less the proportion of the disease. Not all have calcium and phosphorus metabolism disorders can produce calcification. Some people analyzed a group of patients, genetic factors accounted for 5% of nervous system diseases 29%, HPT 37%, the other 37%. In this paper, a report of 3 cases, the pathogenesis of this disease are discussed. Three patients are all adult males, all have a history of meningitis, 11 to 36 years after the disease, manifested as a generalized epileptic seizures or a