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目的探讨血尿酸(BUA)、尿微量白蛋白水平与2型糖尿病颈动脉内膜病变的关系。方法 100例2型糖尿病患者,根据患者是否合并颈动脉内膜病变分为观察组(55例)与参考组(45例),观察两组患者BUA、胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)、尿白蛋白排泄率(UAER)水平。结果两组患者TC、TG、HDL、LDL水平比较差异无统计学意义(P>0.05);BUA、UAER水平比较差异具有统计学意义(P<0.05)。结论血尿酸、尿微量白蛋白水平与2型糖尿病颈动脉内膜病变之间有着显著关系,可作为病情观察的有效指标,一旦出现异常,需要考虑为颈动脉内膜病变。
Objective To investigate the relationship between serum creatinine (BUA), urinary microalbumin and carotid artery intima in type 2 diabetic patients. Methods 100 patients with type 2 diabetes mellitus (T2DM) were divided into observation group (55 cases) and reference group (45 cases) according to whether they had carotid endarterosis or not. The levels of BUA, TC, , High density lipoprotein (HDL), low density lipoprotein (LDL) and urinary albumin excretion rate (UAER). Results There was no significant difference in TC, TG, HDL and LDL levels between the two groups (P> 0.05). There was significant difference in BUA and UAER between the two groups (P <0.05). Conclusion There is a significant relationship between serum uric acid and urine microalbumin levels and carotid artery endothelium lesions in type 2 diabetes mellitus, which can be used as an effective indicator of disease observation. Once an abnormality occurs, carotid endarterial lesions need to be considered.