论文部分内容阅读
目的讨论梅毒母婴传播的预防措施。方法对1400例孕妇进行妊娠期梅毒螺旋体抗体(抗-TP)检测,对已确诊的妊娠合并梅毒患者进行规范化治疗,在早孕三个月、晚孕三个月各给予一个疗程的治疗,苄星青霉素240万u分两侧臀部肌注,每周1次,共3次为1个疗程。或普鲁卡因青霉素80万u肌注,每日1次,连用10~15天为1个疗程,对青霉素过敏者用红霉素500 mg,每日4次口服,连续15天为1个疗程。孕妇治疗期间每月应检测UDRL或RPR滴度到分娩(如滴度上升,可间隔两到四周追加一个疗程)。结果妊娠者同时存在梅毒,会导致严重妊娠异常结局的发生,如流产、死胎等。在第一次孕检时,需要对妊娠者施以常规性的梅毒产前筛查。对于阳性者,及时采取规范的措施进行治疗,对母婴垂直传播进行有效地阻断。结论梅毒的筛查及母婴阻断可降低新生儿的发病率,提高围生期保健质量,达到实现优生优育的目的。
Objective To discuss the preventive measures of mother-to-child transmission of syphilis. Methods Pregnant women with syphilis of pregnancy were tested for anti-Treponema pallidum antibody (anti-TP) in 1400 pregnant women. Patients with confirmed pregnancy complicated with syphilis were treated with standardized therapy. One course of treatment was given in three months of pregnancy and three months of pregnancy. Penicillin 2.4 million u points hip muscle injection on both sides, once a week, a total of 3 times for a course of treatment. Or procaine 800000 u penicillin intramuscular injection, once daily, once every 10 to 15 days for a course of treatment, those who are allergic to penicillin erythromycin 500 mg, 4 times a day orally for 15 days for a Course of treatment. Pregnant women should be monitored monthly UDRL or RPR titers until delivery (such as increased titer, an additional interval of two to four weeks of treatment). The results of pregnancy syphilis exist at the same time, will lead to serious abnormal pregnancy outcomes, such as miscarriage, stillbirth and so on. At the first pregnancy test, a routine prenatal screening of syphilis is required for pregnancy. For those who are positive, timely and normative measures for treatment, vertical transmission of mother and child to effectively block. Conclusion The screening of syphilis and maternal and infant block can reduce the incidence of newborns, improve perinatal health care quality, and achieve the purpose of prenatal and postnatal care.