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目的探讨女性青春期前患腮腺炎对成年后生殖系统的不良影响。方法回顾性分析1510例接受体外受精-胚胎移植的不孕女性中,青春期前患腮腺炎的成年不孕女性生殖系统疾病的患病率及试管婴儿技术助孕结局。结果有腮腺炎病史的不孕病人行体外受精的妊娠率为22%(45/205),对照组为29.7%,P=0.024。青春期前患腮腺炎患者中成年后子宫内膜异位症、卵巢囊肿的患病率分别为19.57%、23.90%,有腮腺炎病史未合并此类疾病的分别为13.1%、11.24%,P=0.00。腮腺炎病史合并输卵管手术史、卵巢手术史、子宫手术史者分别占28.31%、41.1%、8.68%,分别高于无腮腺炎病史的患者,P<0.05。结论女性青春期前患腮腺炎与成年后的生殖系统疾病及手术有相关性,需要对青春期前患腮腺炎女性的生育状况加以重视。
Objective To investigate the adverse effects of female adolescent mumps on adult reproductive system. Methods The prevalence of reproductive system diseases in adult infertile women with adolescent mumps and fertilization outcome of IVF in 1510 infertile women receiving in vitro fertilization and embryo transfer were retrospectively analyzed. Results Infertility patients with a history of mumps had a pregnancy rate of 22% (45/205) for in vitro fertilization compared with 29.7% in the control group (P = 0.024). Adolescent mumps in adult patients with endometriosis, the prevalence of ovarian cysts were 19.57%, 23.90%, mumps without the history of such diseases were 13.1%, 11.24%, respectively, P = 0.00. Mumps history combined tubal surgery history, ovarian surgery history, uterine surgery history accounted for 28.31%, 41.1%, 8.68%, respectively, higher than those without mumps history, P <0.05. Conclusion Female adolescent mumps and adult reproductive system diseases and surgery are related, the need for adolescent mumps female reproductive status to be paid attention to.