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目的:探讨药师对产科医生用药行为的干预,对于提高剖宫产围手术期抗菌药应用合理性的效果。方法:随机抽取我院2011年第2季度(干预前)、第4季度(干预中)和2012年第2季度(干预后)剖宫产病例各50份,比较各时间段围手术期应用抗菌药各项指标的变化,评估干预效果。结果:经过2阶段干预后,我院剖宫产围手术期抗菌药应用各项监测指标较干预前明显改善,合理使用率从干预前的10%提高到70%(P<0.01),抗菌药使用强度(AUD)也从干预前的97.51降至46.58。结论:药师采取综合干预管理模式可行,可有效提高剖宫产围手术期抗菌药合理应用率。
OBJECTIVE: To investigate the intervention of pharmacists on the medication behavior of obstetricians, and to improve the rationality of antibacterials application in cesarean section during perioperative period. Methods: Fifty cases of cesarean section in our hospital from the second quarter of 2011 (pre-intervention), the fourth quarter (mid-term of intervention) and the second quarter of 2012 (post-intervention) were randomly selected. Changes in various indicators of drugs to assess the effect of intervention. Results: After 2 stages of intervention, the monitoring indicators of perioperative antibacterials application during cesarean section in our hospital were significantly improved compared with those before intervention. The reasonable utilization rate increased from 10% before intervention to 70% (P <0.01) The intensity of use (AUD) also decreased from 97.51 before intervention to 46.58. Conclusion: It is feasible for pharmacists to take comprehensive intervention management mode, which can effectively improve the reasonable utilization rate of antibacterials in cesarean section perioperative period.