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目的:分析研究成人难治性部分性癫痫患者接受常规治疗基础上加用妥泰治疗的方法以及效果,为临床提供依据。方法:回顾性分析2014年8月到2015年8月成人难治性部分性癫痫患者资料80例,将80例患者随机分为观察组和对照组,每组分别40例,对照组患者进行常规治疗,观察组在常规治疗基础之上加用妥泰进行治疗,记录观察组和对照组患者治疗效果和不良反应发生情况,将结果进行统计学分析。结果:观察组患者治疗总有效率明显高于对照组患者(P<0.05),具有统计学意义;观察组和对照组患者没有发生显著不良反应,两组患者均存在一定胃肠道不适,少数患者出现头晕以及头昏现象,两组患者不良反应机体可以耐受。结论:针对成人难治性部分性癫痫患者在常规治疗基础上加用妥泰治疗效果明显,能够有效改善其体征以及临床症状,减少癫痫发作的次数,患者治疗期间没有出现明显不良反应,应该在临床中大力推广使用。
Objective: To analyze the method and effect of topiramate treatment on the basis of routine treatment of adult patients with refractory partial epilepsy, and to provide evidence for clinical treatment. Methods: A retrospective analysis of 80 patients with adult refractory partial epilepsy from August 2014 to August 2015, 80 patients were randomly divided into observation group and control group, 40 cases in each group, the control group patients were routine The treatment group and the observation group were treated with topotecan on the basis of conventional treatment. The treatment effect and adverse reactions of the observation group and the control group were recorded, and the results were statistically analyzed. Results: The total effective rate of observation group was significantly higher than that of control group (P <0.05), with statistical significance; there was no significant adverse reactions in observation group and control group, both groups had certain gastrointestinal discomfort, a few Patients with dizziness and dizziness phenomenon, two groups of patients with adverse reactions can tolerate. Conclusion: The treatment of adult refractory partial epilepsy patients with topiramate on the basis of routine treatment is effective, which can effectively improve the signs and clinical symptoms and reduce the number of seizures. There are no obvious adverse reactions during the treatment, Promote the use of clinical.