多聚ADP-核糖[(ADPR)_n]是六十年代新发现的普遍存在于真核细胞核内的一类核酸大分子。它由一种特异的核内酶——多聚ADP-核糖聚合酶或称ADP-核糖基转移酶(AD PRT)以尼克酰胺腺嘌呤二核苷酸(NAD)为底物催化生成。近二十年来,各国学者对(ADPR)_n的结构,功能进行了广 Polymeric ADP-ribose [(ADPR) _n] is a newly discovered class of nucleic acid macromolecules ubiquitously found in eukaryotic nuclei of the sixties. It is catalyzed by nicotinamide adenine dinucleotide (NAD) catalyzed by a specific nuclear enzyme, poly ADP-ribose polymerase or ADPR-ribosyltransferase (AD PRT). In the recent two decades, the scholars and scholars in various countries have made extensive efforts on the structure and function of (ADPR) _n