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虽然血卟啉衍生物已在临床上用来治疗恶性实体瘤,但仍有许多问题尚不清楚。因此为了评价血卟啉衍生物的治癌效应必须了解血卟啉衍生物对血管内皮的作用。作者用光学显微镜和电子显微镜观察了DBA/2H_2小鼠的SMT-F癌用血卟啉衍生物加激光处理后有最初几小时癌组织血管的变化,光学
Although hematoporphyrin derivatives have been used clinically to treat malignant solid tumors, many problems remain unclear. Therefore, in order to evaluate the therapeutic effect of hematoporphyrin derivatives, it is necessary to understand the effect of hematoporphyrin derivatives on vascular endothelium. The authors observed the changes of the blood vessels of the cancer tissue in the first few hours of the SMT-F cancer with hematoporphyrin derivatives plus laser treatment in DBA/2H_2 mice using optical microscope and electron microscope.