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慢性冷凝集病患者体内的冷凝集素通常是IgMk 抗I自身抗体。本文报导1例慢性冷凝集男性患者(现年40岁),其冷凝集素由IgG和IgM抗I抗体组成。入院前,患者已有3年冷凝集病史。因发现溶血性贫血加重以及深静脉血栓而入院,呈现发热、面容灰白、轻微黄疸、左腿肿胀等症状。化验结果:Hb 6.8g/dl,红细胞比积22%,网织红细胞14.3%,LDH2740,直接抗人球试验仅与抗-C_8d抗血清发生阳性反应,胆红素血和血红蛋白尿均阳性,诊断为深部静
Cold agglutinating disease in patients with cold agglutinin is usually IgMk anti-I autoantibodies. This article reports 1 case of chronic cold condensing male patients (aged 40 years old), the cold agglutinin by IgG and IgM anti-I antibody. Before admission, the patient had a history of 3 years of cold coagulation. Because of increased hemolytic anemia and deep venous thrombosis and admission, showing fever, pale face, mild jaundice, left leg swelling and other symptoms. The results of the assay were as follows: Hb 6.8g / dl, hematocrit 22%, reticulocyte 14.3%, LDH 2740, direct anti-human test only positive with anti-C_8d antiserum, positive bilirubin and hemoglobin urine, diagnosis For deep quiet