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目的观察炔雌醇环丙孕酮联合克罗米芬治疗多囊卵巢综合征(PCOS)伴不孕症的临床效果。方法将PCOS伴不孕症患者50例随机分为观察组和对照组各25例,对照组给予克罗米芬治疗,观察组在对照组治疗的基础上给予炔雌醇环丙孕酮治疗,比较2组治疗前后孕酮水平及临床疗效。结果治疗前2组孕酮水平比较差异无统计学意义(P>0.05),治疗后2组患者黄体中期孕酮水平均显著上升(P<0.05),且观察组显著优于对照组(P<0.05)。观察组总有效率为96.0%高于对照组的80.0%,差异有统计学意义(P<0.05)。结论炔雌醇环丙孕酮联合克罗米芬治疗PCOS伴不孕症临床效果显著,值得临床推广应用。
Objective To observe the clinical effect of ethinylestradiol and cyproterone combined with clomiphene in treating polycystic ovary syndrome (PCOS) with infertility. Methods 50 cases of PCOS with infertility were randomly divided into observation group and control group, 25 cases in the control group were treated with clomiphene, the observation group was given ethinyl estradiol cyproterone treatment on the basis of the control group, compared with 2 The level of progesterone before and after treatment and its clinical efficacy. Results There was no significant difference in the levels of progesterone between the two groups before treatment (P> 0.05). The levels of progesterone in the mid luteal phase of two groups were significantly increased after treatment (P <0.05), and the observation group was significantly better than the control group (P < 0.05). The total effective rate in the observation group was 96.0%, which was significantly higher than that in the control group (80.0%, P <0.05). Conclusion Ethinylestradiol, cyproterone combined with clomiphene for the treatment of PCOS with infertility has a significant clinical effect and is worthy of clinical application.