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目的:探讨不同年龄段急性脑梗死患者血浆同型半胱氨酸(Hcy)水平及临床意义。方法:将538例急性脑梗死患者按年龄分为A组(年龄40~49岁)、B组(年龄50~59岁)、C组(年龄60~69岁)、D组(年龄70~79岁)和E组(年龄80~89岁)。分析各年龄段患者血浆Hcy水平、伴随疾病与急性脑梗死的发病关系。结果:各年龄段脑梗死患者血浆Hcy水平均高于对照组;A组和E组血浆Hcy水平明显高于C组,差异有统计学意义,P<0.05。结论:血浆Hcy水平的升高与各年龄段急性脑梗死发病均有关,与40~49岁和80~89岁的患者关系更密切。
Objective: To investigate the plasma homocysteine (Hcy) levels in patients with acute cerebral infarction at different ages and their clinical significance. Methods: 538 patients with acute cerebral infarction were divided into three groups according to their ages: group A (age 40-49), group B (age 50-59), group C (age 60-69), group D (age 70-79 Years old) and E group (aged 80 ~ 89 years old). Analysis of plasma Hcy levels in patients of all ages, with the disease and the incidence of acute cerebral infarction. Results: Plasma Hcy levels in patients with cerebral infarction at various ages were significantly higher than those in the control group. Plasma Hcy levels in groups A and E were significantly higher than those in C group (P <0.05). CONCLUSIONS: Elevated plasma levels of Hcy are associated with the incidence of acute cerebral infarction in all age groups, and are more closely related to patients 40 to 49 and 80 to 89 years of age.