论文部分内容阅读
目的分析胆道癌、胆石症、对照人群血脂含量。方法测定１７７例胆道癌，２１３例胆石症，１８７例对照人群六项血脂指标，并进行分析比较。结果胆道癌的甘油三酯（ＴＧ）、低密度脂蛋白（ＬＤＬ）、载脂蛋白Ｂ（ＡｐｏＢ）明显高于胆石症和对照人群，差异非常显著（Ｐ值分别＜０．０００１，＜０．０５，＜０．０００１）；胆道癌的高密度脂蛋白（ＨＤＬ）明显低于胆石症和对照人群（Ｐ＜０．０００１）；胆道癌、胆石症载脂蛋白Ａ（ＡｐｏＡ）高于对照人群，差异非常显著（Ｐ＜０．０１）。三组人群间总胆固醇（ＴＣ）无显著差异。结论胆道癌、胆石症、对照人群血脂含量存在明显差异，并显示胆道癌比胆石症存在明显的高血脂倾向。
Objective To analyze the blood lipid levels in patients with biliary tract cancer, cholelithiasis, and control subjects. Methods A total of 177 cases of biliary tract cancer, 213 cases of cholelithiasis, and 187 control subjects were measured for six lipid profiles and analyzed and compared. Results The levels of triglyceride (TG), low-density lipoprotein (LDL) and apolipoprotein B (ApoB) in biliary tract cancer were significantly higher than those in cholelithiasis and control population (P<0.0001, <0. 05,<0.0001); high-density lipoprotein (HDL) in biliary tract cancer was significantly lower than in cholelithiasis and control population (P<0.0001); apolipoprotein A (ApoA) in cholangiocarcinoma and cholelithiasis was higher than that in control group. The difference was very significant (P<0.01). There was no significant difference in total cholesterol (TC) between the three groups. Conclusion There are significant differences in blood lipid levels between patients with biliary tract cancer, cholelithiasis, and control subjects, and it is shown that biliary tract cancer has a significantly higher cholesterol profile than cholelithiasis.