论文部分内容阅读
用间接ＥＬＩＳＡ法检测５１例病毒性心肌炎患儿血清中柯萨奇Ｂ组病毒（ＣＶＢ）ＩｇＧ、ＩｇＭ，结果ＣＶＢ－ＩｇＭ≥１∶１００（＋）２１例，占４１．２％。３５例非心肌炎组患儿ＣＶＢ－ＩｇＭ≥１∶１００（＋）２例，占５．７％。经统计学处理，两者有非常显著差异（Ｐ＜０．０１）。说明ＣＶＢ是合肥地区病毒性心肌炎的主要病原；ＣＶＢ－ＩｇＭ检测，方法简便，准确可靠，具有早期诊断价值。ＩｇＭ阳性组病程均在两个月以内，９０．５％有明确的上呼吸道或肠道感染史，ＳＴ－Ｔ改变占２８．６％，与ＩｇＭ阴性组比较差异显著（Ｐ＜０．０５）；ＩｇＭ阳性组心脏扩大、心功能不全均较阴性组多，但经χ２检验没有差异（Ｐ＞０．０５）；ＩｇＭ阳性组与阴性组在心律紊乱、酶学异常上没有差异。
The serum levels of Coxsackie B virus (CVB) IgG and IgM in 51 children with viral myocarditis were detected by indirect ELISA. The results showed that 21 cases (41.2%) had CVB-IgM≥1: 100 (+). 35 cases of non-myocarditis group CVB-IgM≥1: 100 (+) in 2 cases, accounting for 5.7%. Statistically, the two have very significant differences (P <0.01). CVB is the main cause of viral myocarditis in Hefei area; CVB-IgM detection, the method is simple, accurate and reliable, with early diagnostic value. The IgM positive group had a history of less than two months, 90.5% had a clear history of upper respiratory tract or intestinal infection, and 28.6% of ST-T changes, which was significantly different from that of the IgM negative group (P <0.05) ; IgM positive group had enlarged heart and cardiac insufficiency were more than negative group, but there was no difference by χ2 test (P> 0.05). There was no difference between the IgM positive group and the negative group in arrhythmia and enzyme abnormalities.