巯甲丙脯酸引起肉眼血尿一例

来源 :中国循环杂志 | 被引量 : 0次 | 上传用户:chaoyuemengxiang2009
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患者,男,61岁农民。因头晕、胸闷一年于1985年10月10日入院。体验:BP190/110mmHg,心界略向左下扩大,心尖区闻及Ⅱ级收缩期杂音,肺及腹部、肛诊前列腺均无异常。血、尿、大便常规检查正常。结合心电图等所见符合高血压病Ⅱ期。入院后服复方降压片等药物联合治疗6天无效,即改服巯甲丙脯酸50mg,每日三次,服药第3日出现无痛性肉眼血尿。尿三杯试验红细胞均(?),血BUN、B超检查肾、输尿管、膀胱无异常。第4日起胸闷、头晕症状减轻,血压稳定于正常范围,肉眼血尿持续22天。当将该药减至25mg,每日三次时,两日后血尿消失,镜检无红细胞。出院后患者治病心切,自动加量至 Patient, male, 61-year-old farmer. Due to dizziness, chest tightness year in October 10, 1985 admission. Experience: BP190 / 110mmHg, the heart slightly expand to the left, apical area smell and Ⅱ systolic murmur, lung and abdomen, anus prostate no abnormalities. Blood, urine, stool routine examination was normal. Combined with electrocardiogram and other findings meet the hypertensive phase Ⅱ. After admission, compound antihypertensive tablets and other drugs combined treatment of 6 days is invalid, that is to change the captopril 50mg, three times daily, medication on the 3rd day painless gross hematuria. Urine three cups of test erythrocytes (?), Blood BUN, B ultrasound examination of the kidney, ureter, bladder no abnormalities. Chest tightness on the 4th day, dizziness symptoms relieved, blood pressure stabilized in the normal range, gross hematuria continued for 22 days. When the drug was reduced to 25mg, three times a day, two days after hematuria disappeared, microscopic examination of red blood cells. Discharged patients after treatment of euthanasia, automatically added to
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