帕金森病(Parkinson’sdisease,PD)是一种常见的中枢神经系统变性疾病,病理上表现为中脑黑质多巴胺能神经元胞质中Lewy小体的形成、多巴胺能神经元丢失和胶质细胞增生。研究显示,Lewy小体也出现在下丘脑、迷走神经背核、交感神经节、副交感神经节及自主神经丛等[1]。70%～89%的 Parkinson’s disease (PD) is a common degenerative disease of the central nervous system, pathologically manifested as the formation of Lewy bodies in the cytoplasm of the substantia nigra dopaminergic neurons, loss of dopaminergic neurons and glial Cell proliferation. Studies have shown that Lewy bodies also appear in the hypothalamus, vagus nerve dorsal nucleus, sympathetic ganglia, parasympathetic ganglia and autonomic plexus [1]. 70% ~ 89%