患者,男性,50岁。右耳流脓20余年,近5～6天脓液增多伴右侧头痛,于1984年2月14日入院。无发烧和呕吐。局部检查:右耳道内有较多粘液脓性分泌物,鼓膜紧张部大穿孔,鼓室内后上方有大肉芽,乳突区无红肿,压痛(+),分泌物细菌培养阴性。入院后次晨体温升高,头痛加剧,不吐,右眼球结膜水肿,眼脸肿胀。自细胞15,600,中性74％,淋巴26％。急诊行右乳突凿开术,术中见鼓窦,乳突腔充满肉芽,鼓窦入口扩大。术前应用青霉素,术后改用红霉素,氯霉素。体温虽渐下降,但眼部症状仍有发展,右眼突出,球结膜水肿,眼球固定,视力光感消失,瞳孔散大至5mm,术后第8天,体温重新上升,白细胞21,800,中性82％,淋巴18％。眶内穿刺(一)。眼底:右眼视乳头边界模糊,色泽红,静脉 Patient, male, 50 years old. Right ear pus more than 20 years, nearly 5 to 6 days increased pus with right headache, in February 14, 1984 admission. No fever and vomiting. Local examination: There are more mucopurulent secretions in the right ear canal, large tympanic membrane perforation, tympanic top large granulation, mastoid swelling, tenderness (+), secretions bacterial culture negative. After admission the next morning temperature, headache worsened, no spit, right eye conjunctival edema, swelling of eyes and face. Since the cells 15,600, 74% neutral, lymph 26%. Emergency right mastoidectomy surgery, see the sinus surgery, mastoid cavity filled with granulation, drum sinus entrance to expand. Preoperative penicillin, postoperative use of erythromycin, chloramphenicol. The body temperature gradually decreased, but the ocular symptoms still developed, prominent in the right eye, conjunctival edema, fixation of the eye, disappearance of visual acuity, mydriasis up to 5mm, postoperative 8th day, body temperature rose again, WBC 21,800, neutral 82%, lymphatic 18%. Orbital puncture (a). Fundus: the right eye papilla border blurred, red color, vein