患者女,61岁。左侧面颊部淡黄色质硬斑块缓慢增大3年。皮肤科情况:左侧面颊部见约2cm×1.5cm大小斑块,轻度隆起,质地坚硬。皮损组织病理示:真皮内见多量由基底样细胞组成的瘤团,瘤细胞核大、浆少、染色嗜碱,周围细胞呈栅栏状排列,并见收缩间隙,团块周围间质胶原纤维增生。诊断为硬斑病样型基底细胞癌。 Female patient, 61 years old. The left cheek pale yellow hard plaque increased slowly for 3 years. Dermatology: the left side of the cheek see about 2cm × 1.5cm size plaque, mild bulge, hard texture. Histopathological examination of the lesion showed that a large number of tumorous masses composed of basal-like cells were seen in the dermis. The tumor nuclei were large, the pulp was small, the staining was basophilic, the surrounding cells were arranged in a palisade pattern, and the systolic spaces were observed. Collagen fibrosis around the mass . Diagnosis of sclerotia-like basal cell carcinoma.