３０只出生３日内乳猪，随机分为不同缺氧缺血时间及正常对照组，结果显示乳猪缺氧缺血６０分钟出现明显缺氧缺血脑损伤表现。不同缺氧缺血时间的脑组织病理观察发现：各组均出现脑水肿，但３０分钟以上最明显。３０分钟组及６０分钟组均可见脑软化，脑室、脑实质及蛛网膜下腔出血，但以６０分钟组发生率最高，病变更显著。 30 piglets born within 3 days were randomly divided into different hypoxic-ischemic time and normal control group, the results showed that hypoxia-ischemia in pigs 60 minutes obvious hypoxic-ischemic brain damage performance. Histopathological examination showed that cerebral edema occurred in all groups, but the most obvious was in more than 30 minutes. Cerebral softening, ventricular, intraparenchymal and subarachnoid hemorrhage were seen in the 30-minute and 60-minute groups, but the incidence was highest in the 60-minute group and the lesions were more pronounced.