患者男,19岁。因门静脉高压、肝硬化失代偿期4个月前行同种异体原位肝移植(不含胆囊),4个月中曾多次出现排异反应,经强地松龙冲击治疗得以控制。半月前,病人出现厌油,乏力,巩膜中度黄染,皮肤轻度黄染,大便呈浅白色,并有逐渐加重趋势。体格检查:血压15/10kPa(1kPa=7.5mmHg),心率96次/分,体温36.5℃,心、肺、腹部检查无异常,AST 83U、ALT75U、蛋白总量52g/L、白蛋白52g/L、胆红素总量658.6μmol/L、 Male patient, 19 years old. Due to portal hypertension, cirrhosis of the decompensation 4 months ago allogeneic orthotopic liver transplantation (without gallbladder), 4 months have repeatedly rejected the reaction, after the treatment of prednisolone can be controlled. Half a month ago, the patient appeared tired of oil, fatigue, moderate yellow sclera stained skin mild yellow dye, pale stool was white, and gradually increase the trend. Physical examination: blood pressure 15 / 10kPa (1kPa = 7.5mmHg), heart rate 96 beats / min, body temperature 36.5 ℃, heart, lung and abdominal examination were normal, AST 83U, ALT75U, total protein 52g / L, albumin 52g / L , Total bilirubin 658.6μmol / L,