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目的:探讨复方甘草酸苷注射液治疗新生儿高胆红素血症临床效果。方法:将136例高胆红素血症患者随机分为治疗组和对照组各68例,两组均给予常规治疗,治疗组静滴复方甘草酸苷注射液3 ml/kg,1次/d,5~7 d为1个疗程;对照组静滴苦黄注射液1 ml/kg,1次/d,5~7 d为1个疗程。治疗结束后复查肝功能及血生化。结果:治疗组1个疗程后,总胆红素、AST、GGT下降值与对照组比较差异有统计学意义(P<0.01),治愈率、平均住院日及医疗费用与对照组比较差异有统计学意义(P<0.01)。结论:复方甘草酸苷注射液对治疗新生儿高胆红素血症有效,较苦黄注射液疗效快,治愈率高、住院时间短,医疗费用低。
Objective: To investigate the clinical effect of compound glycyrrhizin injection on neonatal hyperbilirubinemia. Methods: 136 cases of hyperbilirubinemia patients were randomly divided into treatment group and control group, 68 cases, both groups were given conventional treatment, the treatment group intravenous compound glycyrrhizin injection 3 ml / kg, 1 / d , 5 ~ 7 d for a course of treatment; control group intravenous infusion of Kuhuang injection 1 ml / kg, 1 / d, 5 ~ 7 d for a course of treatment. After treatment, check liver function and blood biochemistry. Results: After 1 course of treatment, the total bilirubin, AST, GGT decreased compared with the control group, the difference was statistically significant (P <0.01), the cure rate, average length of stay and medical costs compared with the control group statistics Significance (P <0.01). Conclusion: Compound glycyrrhizin injection is effective in treating neonatal hyperbilirubinemia. It has faster curative effect than Kuhuang injection, high cure rate, short hospital stay and low medical cost.