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对于不能手术的肺癌在治疗上仍是一个难题。以往采用化疗加放疗或单纯化疗可以起到一定的缓解作用,但静脉滴注抗癌药物后,进入肺癌组织的浓度仍较低,杀伤癌细胞效果较差,而全身副作用却很大,病人难以忍受,因之也难达到满意疗效。1964年Soderberg从支气管动脉内直接灌注氮芥治疗肺癌以来,国内外都在不断改进和开展中。我院从1988年以来对10例确诊肺癌而不能手术的病人,采用经股动脉插管从支气管动脉内灌注抗癌药物进行治疗,均收到较为满意疗效,今介绍如下: 临床资料 一、一般资料:男7例,女3例。年龄:39~65岁。左侧6例,右侧4例。内7例经纤支镜作病
The treatment of inoperable lung cancer is still a problem. In the past, chemotherapy and radiotherapy or chemotherapy alone could have some relief effect. However, after infusion of anti-cancer drugs, the concentration of lung cancer is still low. The effect of killing cancer cells is poor, but the systemic side effects are very large. Endure, because it is difficult to achieve satisfactory results. Since Soderberg instilled nitrogen mustard directly from the bronchial arteries in 1964 to treat lung cancer, both domestic and international are constantly improving and developing. In our hospital since 1988, 10 cases of patients diagnosed with lung cancer who could not be operated on were treated with transfemoral cannula infusion of anticancer drugs from bronchial arteries. All received satisfactory results. This is described as follows: Clinical data I. General Data: 7 males and 3 females. Age: 39 to 65 years old. There are 6 cases on the left side and 4 cases on the right side. 7 cases of fiberoptic bronchoscopy