Effects of Resveratrol on Membrane Potential and Calcium Ions of HA-VSMC

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[Objective]To study the effects of resveratrol on membrane potential and calcium ions of human vascular smooth muscle cell(T /G HAVSMC).[Method]VSMC was labeled with DiBAC4(3) and Fluo-3-AM,respectively;and then the changes of membrane potentials and the concentration of calcium ions were detected by flow cytometer.[Result] Resveratrol made the VSMC membrane potentials less negative or depolarized,and it increased the concentration of intracellular free calcium.[Conclusion] Resveratrol could depolarize the membrane potentials and increase the concentration of intracellular free calcium in HA-VSMC. [Objective] To study the effects of resveratrol on membrane potential and calcium ions of human vascular smooth muscle cell (T / G HAVSMC). [Method] VSMC was labeled with DiBAC4 (3) and Fluo-3-AM, the changes of membrane potentials and the concentration of calcium ions were detected by flow cytometer. [Result] Resveratrol made the VSMC membrane potentials less negative or depolarized, and it increased the concentration of intracellular free calcium. [Conclusion] Resveratrol could depolarize the membrane potentials and increase the concentration of intracellular free calcium in HA-VSMC.
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