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自1991年4月以来,通过对报告的急性弛缓性麻痹(AFP)病例和病人接触者的粪便标本检测,山东省未发现脊髓灰质炎(脊灰)野病毒。自1992年开始引用世界卫生组织(WHO)的诊断标准,每年均有一定数量的临床确诊脊灰病例。WHO提出,分离到野病毒作为唯一的确诊依据,在消灭脊灰后期很有必要。卫生部提出,在WHO推荐标准基础上结合专家组诊断意见,能保证临床符合病例具有较高特异性。山东省所有确诊脊灰病例均由专家组诊断,对专家组诊断的临床脊灰病例仍应引起高度重视,以便综合分析是否有野病毒引起的可能。15岁以下儿童非脊灰AFP病例报告发病率已连续3年达到1/10万的指标,AFP病例的粪便标本采集率达到80.2%,与医院的及时报告率提高有密切关系。受病例麻痹到就诊的时间间隔和其它客观因素的影响,麻痹两周内采集到合格粪便标本的期望比例为93.5%,市、县两级医院能否及时报告和采便是提高监测系统敏感性和质量的关键。报告AFP病例中经省专家组诊查剔除非AFP病例191例,占报告病例的31.2%。在强调监测敏感性的同时,也应注意提高监测工作的特异性,以全面提高监测工作的质量。
Since April 1991, no poliovirus (polioviruses) have been found in Shandong Province for reported cases of acute flaccid paralysis (AFP) and stool specimens from patient contacts. Since 1992, the World Health Organization (WHO) diagnostic criteria have been quoted with a certain number of clinically confirmed cases of polio each year. The WHO proposed that isolation of wild virus as the sole basis for diagnosis is necessary to eradicate polio. Ministry of Health proposed that combined with expert opinion on the basis of the WHO recommended criteria, to ensure that the clinical line with a higher specificity of the case. All cases of confirmed polio in Shandong Province are diagnosed by the expert group, and the clinical polio cases diagnosed by the expert group should still be given high priority in order to comprehensively analyze the possibility of wild-type virus. The incidence of non-polio AFP cases in children under 15 years of age has reached 1/100000 for three consecutive years, and the collection rate of stool samples in AFP cases reached 80.2%, which is closely related to the timely reporting rate of hospitals. Influenced by the paralyzed patient visits and other objective factors, the expected percentage of qualified stool samples collected within two weeks of paralysis was 93.5%. Whether the hospitals in cities and counties can timely report and pick up the samples is to improve the monitoring system The key to sensitivity and quality. In the report, 191 cases of AFP cases were excluded from the AFP case study by the provincial expert group, accounting for 31.2% of the reported cases. While emphasizing the sensitivity of monitoring, attention should also be paid to improving the specificity of monitoring so as to comprehensively improve the quality of monitoring.