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目的了解克州人民医院头孢菌素类药物的临床应用情况及趋势,为临床合理用药提供科学依据。方法以限定日剂量(DDD)、日用药费用(DDC)、用药频度DDDs以及药物利用指数为指标,对2008~2010年克州人民医院头孢菌素类药物的使用情况进行分析。结果第一代头孢菌素用量逐年减少,第二、三代头孢菌素用量占临床治疗的主导地位,第四代头孢菌素用量逐年增加。结论该医院头孢菌素类药物应用日益趋于合理,但仍需进一步加强抗菌药物合理使用的宣传和监管,应控制第三代头孢菌素及其复方制剂类药物的用量。
Objective To understand the clinical application and trends of cephalosporins in the People’s Hospital of Kezhou and provide a scientific basis for clinical rational drug use. Methods The DDD, DDC, DDDs and drug use index were used as indicators to analyze the use of cephalosporins in the state hospital from 2008 to 2010. Results The dosage of the first generation cephalosporins decreased year by year. The second and third generation cephalosporins accounted for the leading position in clinical treatment. The dosage of the fourth generation cephalosporins increased year by year. Conclusion The use of cephalosporins in the hospital is becoming more and more reasonable. However, it is still necessary to further strengthen the publicity and supervision on the rational use of antibacterials and to control the dosage of third-generation cephalosporins and their combination preparations.