在过去的10年中,有许多扩血管药物被用于治疗心力衰竭,其中包括具有扩张外周血管的钙通道阻滞剂硝苯吡啶。然而,其对心脏的后负荷、前负荷及收缩力方面的效应尚有争议。特别在硝苯吡啶对左心室充盈压、对肌力的影响及其相应的神经内分泌效应等方面尚缺乏直接的依据及明确的结果。本文利用导管法获取了硝苯吡啶和硝普钠在上述几方 In the past 10 years, many vasodilators have been used to treat heart failure, including nifedipine, a calcium channel blocker with dilated peripheral vessels. However, its effect on the heart’s afterload, preload, and contractility is controversial. Especially in the nifedipine on the left ventricular filling pressure, the impact of muscle strength and its corresponding neuroendocrine effects and other aspects of the lack of direct basis and clear results. In this paper, the catheter method obtained nifedipine and sodium nitroprusside in the above-mentioned several parties