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目的:评价医院抗菌药物临床使用情况及其经济学指标,为临床合理用药与管理提供参考。方法:采用回顾性方法,分析与评价医院2011年—2015年抗菌药物品种、销售金额、用药频度(DDDs)、日均费用(DDDc)、使用强度(AUD)及使用率等相关数据。结果:通过抗菌药物使用专项整治,各项控制指标明显下降;品种结构逐年优化;微生物标本检测和细菌耐药监测工作稳步推进,自2014年后,抗菌药物AUD出现回升趋势。结论:医院抗菌药物临床使用基本合理,干预效果较显著,但仍存在一些问题,仍需加强行政干预。
Objective: To evaluate the clinical use of antibacterials in hospital and its economic indicators to provide a reference for clinical rational drug use and management. Methods: A retrospective analysis was conducted to analyze and evaluate the data of antimicrobial agents, sales amount, DDDs, DDDc, intensity of use (AUD) and utilization rate in the hospital from 2011 to 2015. Results: Through the special remediation of antibacterial drugs, the control indexes decreased significantly; the structure of breeds was optimized year by year; the detection of microbial specimens and the monitoring of bacterial resistance were steadily progressed. Since the year of 2014, the rising trend of antimicrobial drugs AUD appeared. Conclusion: The clinical use of antimicrobial agents in hospitals is basically reasonable and the intervention effect is more obvious. However, there are still some problems, and administrative intervention still needs to be strengthened.