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随机搜集AITD83例、GD76例、亚甲炎21例、结甲64例和单甲32例,通过临床表现,甲状腺形态,甲状腺功能,甲状腺抗体及甲状腺超声检查进行分析、比较。结果发现先天性单纯性腋毛缺失与AITD有极密切相关联系,伴腋毛缺失者高达92.77%,伴腋毛稀少者占4.82%。本症候群特点是:①主要见于30～50岁女性的;②甲状腺呈中等度弥漫而不均匀的、≥II°硬度的无痛性甲状腺肿大;③甲状腺超声声像图显示:光点增粗,回声低,分布不均匀,或同伴有血管扩张,血流丰富;④甲状腺抗体、:TPOAb、TgAb显著升高;⑤常伴白细胞减少,肝酶系增高;⑥伴先天性单纯性腋毛缺失。结论伴先天性腋毛缺失的自体免疫性甲状腺疾病有其独立的症群,先天性腋毛缺失可能是这组症群的遗传象征,建议称为腋毛缺失—甲状腺免疫综合征。
Randomly collected AITD83 cases, GD76 cases, 21 cases of methyleneriphritis, 64 cases of tuberculosis and single arm 32 cases, through clinical manifestations, thyroid morphology, thyroid function, thyroid antibodies and thyroid ultrasound examination were analyzed and compared. The results showed that congenital simple axillary hair loss and AITD are closely related, with armpit hair loss as high as 92.77%, with armpit hair scarce accounted for 4.82%. The characteristics of this syndrome are: ① mainly seen in women aged 30 to 50; ② thyroid was moderate and diffuse and uneven, ≥ Ⅱ ° hardness of painless goiter; ③ thyroid ultrasound sonography: thick spots , Low echo, uneven distribution, or companion vasodilation, blood flow; ④ thyroid antibodies, TPOAb, TgAb significantly increased; ⑤ often accompanied leukopenia, increased liver enzymes; ⑥ with congenital simple axillary hair loss. Conclusions The autoimmune thyroid disease with congenital armpit hair loss has its own independent syndrome group. The congenital armpit hair loss may be the genetic symbol of this group of syndromes. It is suggested that the armpit hair loss - thyroid immune syndrome.