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目的分析人乳头瘤病毒(human papillomavirus,HPV)感染在宫颈癌癌前病变筛查中的临床价值,并探讨宫颈癌预防措施。方法随机选取博罗县人民医院检验科2015-04/2016-04自愿接受宫颈癌筛查的80例女性,均行HPV筛查,并进行宫颈组织活检,以病理学诊断结果为准。统计HPV与组织病理学检查结果、不同年龄段HPV阳性率。结果经HPV检查,阳性70例,阴性10例,阳性检出率87.50%,子宫颈上皮内瘤变轻度不典型增生Ⅰ级(CNIⅠ)级以上的有62例。青年组、中年组、老年组HPV阳性率分别为90.91%、92.00%、50.00%,不同年龄段比较,差异具有统计学意义(P<0.05)。结论青、中年女性为HPV感染的高发人群,HPV感染检查在宫颈癌筛查中可降低误诊、漏诊率,提高准确率,为疾病的诊断及治疗提供科学、有效的参考依据,具有重要的临床推广及应用价值。
Objective To analyze the clinical value of human papillomavirus (HPV) infection in the screening of precancerous lesions of cervical cancer and to explore the preventive measures of cervical cancer. Methods Totally 80 female patients who voluntarily received cervical cancer screening from April 2015 to April 2016 were randomly selected for HPV screening and biopsy of cervical tissue. The pathological diagnosis was taken as the criterion. Statistics HPV and histopathological examination results, HPV positive rate of different age groups. Results According to the results of HPV examination, 70 cases were positive and 10 cases were negative, the positive rate was 87.50%. There were 62 cases of cervical intraepithelial neoplasia more than grade Ⅰ (CNI Ⅰ). The positive rate of HPV in young group, middle-aged group and elderly group were 90.91%, 92.00% and 50.00%, respectively. There were significant differences in HPV among different age groups (P <0.05). Conclusions The young and middle-aged women are the high incidence of HPV infection. HPV infection screening can reduce the misdiagnosis and misdiagnosis rate and improve the accuracy rate of cervical cancer screening, and provide a scientific and effective reference for the diagnosis and treatment of the disease. It is important Clinical promotion and application value.