论文部分内容阅读
目的探讨以哮喘或咳嗽为主诉的儿童皮肤点刺试验结果差异。方法选取2005年6月-2008年5月在湖南省儿童医院呼吸免疫专科门诊就诊或住院的以哮喘或咳嗽为主诉的儿童1010例,男640例,女370例,年龄10个月～15岁(平均4.97±2.56岁)。其中以哮喘为主诉儿童686例(哮喘组),年龄(5.41±2.79)岁,以咳嗽为主诉儿童324例(咳嗽组),年龄(4.83±2.50)岁。两组儿童分别进行17种变应原的皮肤点刺试验。结果哮喘组较咳嗽组在粉尘螨、玉米花粉、酵母菌、羽毛、海蜇的皮肤点刺试验阳性率高(P<0.05或0.01),但在棉絮、香烟、艾蒿花粉的皮肤点刺试验阳性率低(P<0.01),其他过敏原皮肤点刺试验结果组间差异无统计学意义(P>0.05)。结论吸入性变应原是引起儿童呼吸道症状的主要病因,且变应原与哮喘症状密切相关,与慢性咳嗽也存在部分相关。
Objective To investigate the differences of skin prick test in children who are mainly suing asthma or cough. Methods From June 2005 to May 2008, 1010 children with asthma or cough were admitted to Hunan Provincial Children’s Hospital for Respiratory Immunology and were hospitalized or hospitalized. There were 640 males and 370 females aged from 10 months to 15 years old (Average 4.97 ± 2.56 years). 686 cases (asthma group), aged (5.41 ± 2.79) years old with asthma, and 324 cases (cough group) were dominated by cough, with an average age of (4.83 ± 2.50) years. Two groups of children were tested for skin irritation of 17 allergens. Results The skin prick test of dust mite, corn pollen, yeast, feather and jellyfish in asthma group was higher than that in cough group (P <0.05 or 0.01), but the skin prick test was positive in cotton wool, cigarette and mugwort pollen (P <0.01). There was no significant difference between the other allergen skin prick test results (P> 0.05). Conclusions Inhalation allergen is the main cause of respiratory symptoms in children. And allergens are closely related to asthma symptoms and partly related to chronic cough.