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作者对265例经内窥镜证实的胃溃疡患者进行了回顾性研究,并追踪2年,以了解由胃溃疡发生胃癌的比例;及鉴别良,恶性溃疡时各项检查的价值等。265例患者在2年随访中37例(14%)发生胃癌。良性溃疡组男、女发病率基本相等(118∶110),而胃癌组以男性占优势(29∶8,P<0.01)。2组发病率均以65~70岁年龄组最高,良性溃疡组平均年龄为58.7岁,恶性溃疡组为62.9岁。恶性溃疡组体重减轻、食欲不振、恶心和/或呕吐等临床表现和具有多种症状(23种)者均较良性组常见,2组消化功能紊乱、腹痛、贫血和胃肠道出血的发生率相近。多数溃
The authors retrospectively studied 265 patients with endoscopically confirmed gastric ulcers and followed them for 2 years to understand the proportion of gastric cancers caused by gastric ulcers; and the value of various examinations for distinguishing between benign and malignant ulcers. In 265 patients, gastric cancer occurred in 37 patients (14%) at the 2-year follow-up. The incidence of men and women in the benign ulcer group was almost equal (118:110), while the gastric cancer group was dominated by men (29:8, P<0.01). The incidence of the two groups were highest in the 65-70 age group, the average age of the benign ulcer group was 58.7 years old, and the malignant ulcer group was 62.9 years old. Clinical manifestations such as weight loss, loss of appetite, nausea, and/or vomiting, and multiple symptoms (23) were more common in the malignant ulcer group than in the benign group. The incidence of digestive disorders, abdominal pain, anemia, and gastrointestinal bleeding was common in the two groups. similar. Most collapses